REVAC-PLUS
For Heat Stress
MINERALSPOULTRY
COMPOSITION:
Each 1 Kg contains:
Vitamin C 3'000 Mg
Potassium chloride 20'000 Mg
Ammonium chloride 20'000 Mg
Sodium bi carbonate 20'000 Mg
Sodium chloride 60'000 Mg
Salicylic acid 5'000 Mg
Dextrose up to 1'000 Gm
Heat stress:
With environmental temperature rising higher than upper critical limit, bird responds in the opposite way.
Peripheral blood circulation (to skin, upper respiratory tract, abdominal muscles. Combs and wattles) increases two to four times. Consequently blood flow to liver intestine, kidneys is reduced
iBirds start panting (increase in respiratory and heart rates)
Birds stretch the body and take lying position closer to litter material and nearer to waterers fans.
Water consumption increases by 1.2 to 3.2 times as per outside temperature.
The first three responses help in sensible heat loss and the last helps in internal cooling of the body system. However, with prolonged exposure to hot weather, these responses will lead to following harmful effects:
A) Reduced blood supply to visceral organs leads to
Poor Wt gain, higher FCR (due to impaired digestion and assimilation)
Enteritis, reversal of body weight due to small intestinal bacterial over growth.
B) Acid base imbalance in the body:
There is loss of CO2 because of continuous panting (hyper ventilation) Which results in increased blood pH (alkaloidosis). Kidneys act to restore the acid base balance by renal exchange of bicarbonates with Cl ion. This results in increased excretion of bicarbonates in urine and retention of Cl in plasma and that leads to systemic acidosis. Thus in heat stress initial alkaloidosis changes to systemic acidosis and birds die of acid shock.
In heat stress, using Ammonium chloride (NH4Cl) + Sodium bicarbonate is helpful, since Ammonium chloride reduces blood pH and Sodium bicarbonate prevents excessive acidosis.
Along with bicarbonates, electrolytes are also excreted in urine because bicarbonates are negatively charged, and Na an K ions (important electrolytes) being positively charged go with it. Loss of electrolytes affects the water balance.
C) Water imbalance in the body:
Normally Water intake + Water formed by oxidative metabolism in body = Water loss through urine, faeces and respiration and evaporation.
In heat stress water loss is more (60% more) through urine and increased respiration. This results in dehydration (decrease in extra cellular fluid level), fall in blood volume, fall in blood pressure and increase in plasma osmolality.
Body reacts to these changes by releasing Renin from kidney cells and that increases thirst. Anti diuretic hormone (vasopressin) is released from pituitary which reduces urine output by increasing water resorption in renal tubules.
Even though birds drink more water, its retention in cells is less because of loss of electrolytes and organic osmolytes (betain, Sorbitol Inositol) as stated above. Negative water balance, prevents internal cooling and hence there is further rise in body temperature.
using electrolytes helps in maintaining water balance in the body cells against extra cellular osmotic gradients.
D) Immune suppression:
In hot weather there is release of corticosteroids from adrenals and also depletion of plasma Vit. C and reduction in lymphocyte count. The effect is immune suppression.
PROPERTIES:
Minerals are a more integral part of all biological functions in Poultry than any other nutrient. These functions include:
Expressions and regulation of genes
Enzyme systems within cells
Osmotic balance
Detoxification
Acid-Base Balance and
Structural tissue e.g. bone
Sodium, Potassium, Chlorine and Bicarbonate form ions. According to their electrical charge ions are either Cations (+) (positive) or Anions (-) (negative).
This equation articulates the importance of Dietary Cation Anion Balance (DCAB) more popularly known as Dietary Electrolyte Balance (DEB).
(Na+ +K+) – (CI-)
Managing the balance of dietary electrolytes is a key factor in maximizing performance in production-limiting environments. The manipulation of DEB must be carefully controlled.
Acid-Base Balance in Poultry Maintenance of acid-base equilibrium is fundamental to life. Enzyme systems, metabolic functions and performance measures depend on this equilibrium. The pH of blood is maintained in the range 7.3 – 7.5 by buffer systems based essentially on HCO3- (bicarbonate ion). Panting respiration is an important reaction in the effort to cool the body by evaporative cooling through loss of water from lungs. This results in metabolic alkalosis due to rapid loss of CO2. Thirst is increased, more urine is excreted and with it key electrolytes. Constant replacement of Sodium, Potassium and Bicarbonate is required.
Increasing DEB values of the by supplementation of Sodium and Potassium improves average daily weight gain of chickens.
Water is the most important nutrient for Poultry. Heat stress increases water consumption by at least five times the normal level in temperate zones.
Exposure to heat stress for long periods suppresses the responsiveness of the immune system. Increased levels of corticosteroids in the blood reduce the activity and population of lymphocytes in the blood.
INDICATIONS:
To prevent heat-stress action.
To control increase of humidity and its suffocative action.
High attitude disease.
Renal functional impairment due to different types of toxicosis.
Decrease the oxidative phosporalization in the mitochondria, causing less heat resulting from metabolism.
Keeping A.T.P from converting to A.D.P, especially in neurons.
TARGET SPECIES:
Chickens, turkeys, rabbits and guinea fowls.
DOSAGE AND ADMINISTRATION:
1: 2Gm / 1 litter water
5 Kg / 1 ton of feed
WARNING& PRECAUTIONS:
Keep this and all medication out of reach of children.
For Veterinary use only .
To be used by Veterinary Prescription Order.
The medicated drinking water should be prepared fresh daily.
During treatment use the medicated water as only source for drinking.
PACKAGE DESCRIPTION:
500 gm plastic bottle 12 bottle / carton pox.
STORAGE CONDITIONS:
Store in dark place, away from direct sunlight under dry conditions at or below 25°C.
Store in closed packing.
WITHDRAWAL TIME:
According national regulations.
