SPIRAVET

(Spiramycin 150 M.I.U.) W.S.P.

ANTIBIOTICSPOULTRY

VETGREEN Co.

COMPOSITION:

Each 100 gm contain:

150 million I.U. Spiramycin as adipate.
Excipients up to 100 Gm.

MODE OF ACTION

Spiramycin reversibly bind to the 50 S subunit of bacterial ribosomes, resulting in blockage of the transpeptidation or translocation reactions, inhibiting protein synthesis and subsequent cell growth. It is primarily bacteriostatic, but may be bactericidal against more sensitive strains when used in high concentrations. Spiramycin also accumulates in high concentrations in the bacterial cell.

ANTIMICROBIAL SPECTRUM:

Act against Gram +ve bacteria .

PROPERTIES:

Spiramycin is a systemic antibiotic related to macrolides group.
At tissue concentrations Spiramycin is bactericidal.
Spiramycin well absorbed from GIT and quickly diffuses to the target tissue (lung–air sac–ovaries) .
Spiramycin is highly concentrated in the respiratory tract and other tissues and macrophages.
Half-life period of spiramycin is between 6.2 and 7.7 hours.
The effect of spiramycin is significantly prolonged than other macrolides.
Spiramycin excreted through bile and urine.
Spiramycin act by interfering with Protein Synthesis.
Spiramycin is most commonly used to treat Mycoplasma infections due Mycoplasma gallisepticum, Mycoplasma synovia and Clostridium perfringens in poultry.

TARGET SPECIES:

Chickens & Turkeys.

INDICATIONS:

For the treatment of CRD (Mycoplasma gallisepticum), infectious synovitis (Mucoplasma synovia) and arthritis

For the treatment of infectious sinusitis (Mycoplasma meleagridis).

DOSAGE:

For Poultry & Turkeys:

60,000 IU / kg B. Wt. (40 gm / 100 liter drinking water ) and treat as follows:

At hatching for 3 - 5 days

At week 3 to 4 for 1 day

At week 8 to 9 for 1 day.

WARNING& PRECAUTIONS:

Keep out of reach of children.
For Veterinary use only .
To be used by Veterinary Prescription Order.
Restricted dose must be followed .
The medicated drinking water should be prepared fresh daily.
During treatment use the medicated water as only source for drinking.
The drinking fountains have to be cleaned and disinfected in order to prevent reinfections .
Eggs produced during medication should not be used for human consumption.

PACKAGE DESCRIPTION:

100Gm metal containers.

STORAGE CONDITIONS:

Store in dark place, away from direct sunlight under dry conditions at or below 25°C.

Store in closed packing.

WITHDRAWAL TIME:

According national regulations .